Why is adequate ventilation important when housing rodents?

• A. To control temperature only
• B. To reduce allergic reactions
• C. Because of ammonia buildup from urine leading to upper respiratory disease
• D. To prevent nesting

Answer: (C)

Adequate ventilation is essential because urine produces ammonia that can accumulate in the cage air. Ammonia irritates the nose and airways and can predispose rodents to upper respiratory disease, conjunctivitis, and overall respiratory distress. By exchanging stale air for fresh air and keeping humidity in a healthy range, ventilation lowers ammonia levels and protects respiratory health. While temperature control and reducing dust/allergens are relevant considerations, the direct health threat linked to cage environments in this context is ammonia from urine. Preventing nesting isn’t related to air exchange.